Pidéo Urolithin A （1143-70-0）
Urolithin A （1143-70-0）spésifikasi
| Ngaran Produk | Bubuk Urolithin A |
| Ngaran kimia | 3,8-dihydroxy-6H-benzo [c] chromen-6-hiji;
3,8-Dihydroxy-6H-dibenzo (b, d) pyran-6-hiji; 3,8-Dihydroxyurolithin; 3,8-dihydroxybenzo [c] chromen-6-hiji; 6H-Dibenzo [b, d] pyran-6-hiji, 3,8-dihydroxy-; 3,8-Hydroxydibenzo-alpha-pyrone; |
| CAS Jumlah | 1143-70-0 |
| InChIKey | RIUPLDUFZCXCHM-UHFFFAOYSA-N |
| seuri | C1=CC2=C(C=C1O)C(=O)OC3=C2C=CC(=C3)O |
| molekular Formula | C13H8O4 |
| molekular Wdalapan | 228.2 g / mol |
| Monoisotopic Massa | 228.042259 g / mol |
| titik lebur | 340-345 ° C |
| titik golak | 527.9 ± 43.0 ° C (Dugaang) |
| Titik kaingetan | 214.2ºC |
| Biologis Satengah-Kahirupan | Urolithin A aya dina cikiih dugi ka 48 jam saatos konsumsi jus dalima. |
| warna | Bodas janten beige |
| Solubility | DMSO: 20 mg / ml, jelas |
| Storage Temperature | 2-8 ° C |
| Application | Dipaké salaku suplemén kadaharan sareng produk anti sepuh, tiasa dianggo pikeun ngirangan peradangan sareng merangan kanker; |
rujukan:
[1] Garcia-Muñoz, Cristina; Vaillant, Fabrice (2014-12-02). "Nasib métabolik tina Ellagitannins: implikasi pikeun Kaséhatan, sareng Perspéktif Panilitian pikeun Pangan Fungsional Inovatif". Ulasan Kritik dina Élmu Pangan sareng Nutrisi. 54 (12): 1584-1598. doi: 10.1080 / 10408398.2011.644643. ISSN 1040-8398. PMID 24580560. S2CID 5387712.
[2] Ryu, D. dkk. Urolithin A nyababkeun mitophagy sareng manjangkeun umur di C. elegans sareng ningkatkeun fungsi otot dina rodénsia. Nat. Med. 22, 879–888 (2016).
[3] "FDA GRAS perhatoskeun GRN No. 791: urolithin A". Administrasi Pangan sareng Narkoba AS. 20 Désémber 2018. Disalin 25 Agustus 2020.
[4] Singh, A.; Andreux, P.; Blanco-Bose, W.; Ryu, D.; Aebischer, P.; Auwerx, J. Rinsch, C. (2017-07-01). "Urolithin A sacara lisan dikaluarkeun aman sareng modulates otot sareng mitokondria biomarker dina lansia". Inovasi dina Sepuh. 1 (suppl_1): 1223–
[5] Heilman, Jacqueline; Andreux, Pénélope; Tran, Nga; Rinsch, Chris; Blanco-Bose, William (2017). "Penilitian kasalametan urolithin A, hiji métabolit anu dihasilkeun ku mikrobiota usus manusa saatos asupan diet tutuwuhan anu diturunkeun ellagitannins sareng asam ellagic". Pangan sareng Toxicology Kimia. 108 (Pt A): 289– doi: 10.1016 / j.fct.2017.07.050. PMID 28757461.
